Platelet transcriptome identifies progressive markers and potential therapeutic targets in chronic myeloproliferative neoplasms.

Cell Rep Med · 2021 · PMC8561315 · PMID 34755136

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highly significantno p-value reported

Next, differential gene expression analysis (DGEA), as shown in a volcano plot ( Figures 2 B and 2C), efficiently distinguished each of the MPN subtypes and resulted in highly significant expression signatures (adjusted p value/FDR < 0.05) with 2634 genes differentially regulated in ET (1364 up and 1269 down), 4398 in PV (2098 up and 2300 down), and 6648 in MF (3965 up and 2683 down).

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