SepA Enhances <i>Shigella</i> Invasion of Epithelial Cells by Degrading Alpha-1 Antitrypsin and Producing a Neutrophil Chemoattractant.

mBio · 2021 · PMC8561385 · PMID 34724811

Europe PMC DOI

hedged sentences

0.0571

closest p · 1.1× alpha

0.0571

boldest claim

The sentences

a pronounced trendP = 0.0571so close (0.05 < p ≤ 0.1)

In the current work, we also detected a pronounced trend in the reduction ( P = 0.0571) of PMN migration after infecting T84 cells in the absence of AAT with the Δ sepA strain compared to WT Shigella .

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approached but did not reach significanceno p-value reported

We believe that this trend approached but did not reach significance because of the modifications made to the infection model.

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