Inhibition of nonsense-mediated decay rescues p53β/γ isoform expression and activates the p53 pathway in MDM2-overexpressing and select p53-mutant cancers.

J Biol Chem · 2021 · PMC8569473 · PMID 34481841

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an increasing trendno p-value reported

We observed a significant increase in the mRNA expression of p53γ and PUMA and an increasing trend in the expression of p53β and GADD45A in NMDi-treated tumors compared with their respective vehicle-treated controls ( Fig.

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