Barely Significant
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Sirtuin inhibition is synthetic lethal with BRCA1 or BRCA2 deficiency.

Commun Biol · 2021 · PMC8575930 · PMID 34750509

Europe PMCDOI
1
hedged sentence
0.0020
closest p · 0.0× alpha
0.0020
boldest claim

The sentences

highly significantp = 0.002actually significant
Amongst the highly significant hits identified in the siRNA screen were members of the NAD + -dependent sirtuin deacetylase family; SIRT1 (Sirtuin 1, SF = 0.36, p = 0.002), SIRT3 (Sirtuin 3, SF = 0.41, p = 0.03), SIRT4 (Sirtuin 4, SF = 0.34, p = 0.006), SIRT5 (Sirtuin 5, SF = 0.38, p = 0.007), SIRT6 (Sirtuin 6, SF = 0.33, p < 0.0001) and SIRT7 (Sirtuin 7, SF = 0.38, p = 0.01).

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