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A Review on the Application and Limitations of Administrative Health Care Data for the Study of Acute Kidney Injury Epidemiology and Outcomes in Children.

Front Pediatr · 2021 · PMC8578942 · PMID 34778133

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a decreasing trendno p-value reported
One study in Japan across more than 280 hospitals showed a decreasing trend in crude in-hospital mortality from 45% in 2007 to 36% in 2016 ( 71 ).

also in 47,180 other papers

an increasing trendno p-value reported
Our group found an increasing trend in the incidence of AKI, as well as use of hemodialysis and CRRT among hospitalized children (1 month to 18 years) in Ontario, Canada ( 69 ).

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.