Shift in MSL1 alternative polyadenylation in response to DNA damage protects cancer cells from chemotherapeutic agent-induced apoptosis.

Cell Rep · 2021 · PMC8580136 · PMID 34644577

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

highly significantno p-value reported

The overlap of 2-pA genes with APA shift between the two cell lines was highly significant (proximal shift: 1.4e −68 ; distal shift: 1.3e −82 , hypergeometric test), which indicates that APA shifts in the presence of DNA-damaging agents are not random, and they could be a coordinated response common to cancer cells.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.