Profound synchrony of age-specific incidence rates and tumor suppression for different cancer types as revealed by the multistage-senescence model of carcinogenesis.

There is an extremely significant Spearman’s rank correlation with k for age at peak incidence rate, both model-fitted (both: Spearman’s ρ = 0.74, P = 0.0002, n = 21; female: ρ = 0.68, P = 0.0002, n = 25; male: ρ = 0.73, P = 0.0001, n = 23) and from the SEER data (both: ρ = 0.62, P = 0.003, n = 21; female: ρ = 0.66, P = 0.0003, n = 25; male: ρ = 0.47, P = 0.02, n = 23).

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