NOT-Gated CD93 CAR T Cells Effectively Target AML with Minimized Endothelial Cross-Reactivity.

In the same scRNA-seq datasets, CD123 expression mirrored CD93 on endothelial cell subsets, and endothelial cells exposed to inflammatory cytokines expressed both CD123 and CD38, indicating that a risk for endothelial cell toxicity may be significant for AML targets beyond CD93.

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