A direct comparison of the CD8 + T-cell response against E1 from Ii-E1E2E6E7 and E1E2E6E7 (Mann-Whitney rank-sum) revealed a p-value of 0.06, which is not strictly significant, but strongly indicates a tendency of Ii improving the magnitude of CD8 + T-cells against E1.
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Design and Immunological Validation of <i>Macaca fascicularis</i> Papillomavirus Type 3 Based Vaccine Candidates in Outbred Mice: Basis for Future Testing of a Therapeutic Papillomavirus Vaccine in NHPs.
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