Contribution of analog signaling to neurotransmitter interactions and behavior: Role of transporter-mediated nonquantal dopamine release.

In addition, compared to control, higher doses (2.5 and 5 mg/kg) of MDMA produced a nonsignificant trend to reduce the total duration of social behavior, while morphine increased the total time ( p = 0.0031).

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Apart from a weak trend to decrease social play at the highest dose of 10 mg/kg ( p = 0.3770), the DAT inhibitor GBR‐12909 administered alone at doses of 1, 3, and 10 mg/kg failed to modulate elements of social behavior (Figure 4e ), including passive social behavior ( p = 0.6125), anogenital sniffing ( p = 0.6783), and general social behavior ( p = 0.6702).

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