It may be significant that advanced UBC in men had higher androgen response activity across all luminal subtypes, compared to advanced UBC in women [ 85 ].
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Gender Differences in Urothelial Bladder Cancer: Effects of Natural Killer Lymphocyte Immunity.
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This sex-linked association was highly significant, as it was found in 6 out of 783 X chromosome genes but in zero of 18,055 genes from autosome chromosomes or pseudoautosomal X chromosome regions [ 204 ].