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Population Pharmacokinetics and Pharmacodynamics of Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction.

Clin Pharmacokinet · 2021 · PMC8585847 · PMID 34086190

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a slight trendno p-value reported
Single-dose studies demonstrated close to linear pharmacokinetics of vericiguat for AUC and a slight trend in decreasing C max with increasing doses.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.