Association between proton-pump inhibitors and the risk of gastric cancer: a systematic review with meta-analysis.

Ther Adv Gastroenterol · 2021 · PMC8586163 · PMID 34777575

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a decreasing trendno p-value reported

2 – 5 Nevertheless, there is a decreasing trend in lifetime GC incidence possibly related to a lower burden of HP infection. 6 Proton-pump inhibitors (PPI) are one of the most frequently prescribed drugs worldwide 7 and considered relatively safe.

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