BACH1, the master regulator of oxidative stress, has a dual effect on CFTR expression.

Highly significant peaks of BACH1 occupancy observed at or close to the promoters of several of BACH1-regulated genes including HMOX1 , GCLM , GCLC , hypoxia inducible factor 1 subunit alpha ( HIF1A ) and BACH1 demonstrate the efficacy of this BACH1 antibody in ChIP-seq experiments in both the cell lines ( Supplementary Figure S5 ).

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