Therapeutic Suppression of FAK-AKT Signaling Overcomes Resistance to SHP2 Inhibition in Colorectal Carcinoma.

Front Pharmacol · 2021 · PMC8591248 · PMID 34790119

Europe PMC DOI

hedged sentence

0.0520

closest p · 1.0× alpha

0.0520

boldest claim

The sentences

marginal significancep = 0.052so close (0.05 < p ≤ 0.1)

We further considered the association between p -SHP2 status and the resistance to SHP099 in cells with both BRAF and KRAS wild types and observed only a marginal significance ( p = 0.052) ( Supplementary Figure S2B ).

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