<i>MKK4</i> variants rs3826392 and rs3809728 are associated with susceptibility and clinicopathological features in colorectal cancer patients.

Iran J Basic Med Sci · 2021 · PMC8591758 · PMID 34804420

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0.0580

closest p · 1.2× alpha

0.0580

boldest claim

The sentences

marginally significantP =0.058so close (0.05 < p ≤ 0.1)

Analysis adjustment by age showed that the patients with presence of G/G genotype for the rs3826392 variant have a protective effect for TNM III+IV stages (OR=0.45; 95% CI=0.23-0.87, P =0.027); while, individuals with the T/T genotype for the rs3809728 variant, have a marginally significant difference for TNM III+IV stages (OR=2.28; 95% CI=1.03- 5.03, P =0.058) ( Table 4 ).

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