Barely Significant
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Comparative Physical Study of Three Pharmaceutically Active Benzodiazepine Derivatives: Crystalline versus Amorphous State and Crystallization Tendency.

Mol Pharm · 2021 · PMC8594866 · PMID 33689364

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highly significantno p-value reported
This difference, however, is highly significant in that it confers the Nordazepam derivative the possibility of self-aggregation via hydrogen bonding via the H-functionalization of the nitrogen atom.

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