of borderline significanceP = 0.057
This inversely corresponded to a pronounced difference in osteoclast numbers/mm 2 : group 2 (WT mice with external fixator and concomitant M-CSF therapy) showed lower numbers of osteoclasts/mm 2 than WT mice in group 1 (external fixator without additional M-CSF therapy), this difference was found to be of borderline significance (P = 0.057).