Regional Strain Pattern and Correlation with Cardiac Magnetic Resonance Imaging in Fabry Disease.

This study also highlights another important observation that average GLS value may not truly reflect the early dysfunction seen in regional strain.[ 7 ] As the classic GLS strain value noted in these studies was cumulative data of all segments, a closer observation showed that there may be significant discrepancies in regional strain value between each segment (i.e. overall regional strain of −18% with −30% in apical septal segment but −11.3% in basal and mid inferoseptal segments).

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