Epitope spreading driven by the joint action of CART cells and pharmacological STING stimulation counteracts tumor escape via antigen-loss variants.

J Immunother Cancer · 2021 · PMC8609946 · PMID 34810235

Europe PMC DOI

hedged sentence

0.0572

closest p · 1.1× alpha

0.0572

boldest claim

The sentences

borderline significantp=0.0572so close (0.05 < p ≤ 0.1)

Among the different diversity indices calculated to estimate the TCR repertoire clonality ( online supplemental table S1 ), only the Berger-Parker Index gave a borderline significant difference in blood (p=0.0572) ( online supplemental table S2 ), with the CART-gp75/STING-L group showing the highest value (increase in dominance) ( figure 4D ).

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