Barely Significant
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Anti-obesity drug discovery: advances and challenges.

Nat Rev Drug Discov · 2022 · PMC8609996 · PMID 34815532

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highly significantno p-value reported
Although there was a large and highly significant improvement in lipid metabolism in humans, PF-05231023 failed to improve glucose to any appreciable degree 134 , 135 .

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.