HOMER analysis of differentially accessible union peaks yielded a highly significant enrichment for RUNT (RUNX2, RUNX3), NR (RORC, RORA, RARG), and T-box family (EOMES, T-bet) TF motifs in CD73 + cells, while HMG family TFs (LEF1, TCF1) were the only motif enriched in CD73 − cells ( Figure 4D ).
← all excerpts
The cell-surface 5'-nucleotidase CD73 defines a functional T memory cell subset that declines with age.
1
—
—