AP39 ameliorates high fat diet-induced liver injury in young rats via alleviation of oxidative stress and mitochondrial impairment.

In addition, from the 3rd week to the 7th week of feeding, HFD obviously reduced the food intake of rats, while the food intake of rats with AP39 treatment showed an increasing trend, but it was not significant except for the 5th week ( Fig. 1C ), which was consistent with Jia et al. and Ren et al. ’ studies [ 12 , 24 ].

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