Thus, upregulated UCP3 driven increases in AMPK could be responsible for the reduced Fasn and Acaca (near significance) expression reported in the male KO-HF group in our study through phosphorylation and inhibition of ACACA [ 48 ].
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Sex-Dependent Effects of Eicosapentaenoic Acid on Hepatic Steatosis in UCP1 Knockout Mice.
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