First Episode Psychosis and Schizophrenia Are Systemic Neuro-Immune Disorders Triggered by a Biotic Stimulus in Individuals with Reduced Immune Regulation and Neuroprotection.

Another highly significant GO path enriched in the downregulated network was the “production of miRNAs involved in gene silencing by miRNA”, which may, at least in part, be ascribed to downregulation of DROSHA, which is a ribonuclease (RNase) III family enzyme and plays a key role in miRNA maturation [ 38 ].

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