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Iron, Copper, and Zinc Homeostasis: Physiology, Physiopathology, and Nanomediated Applications.

Nanomaterials (Basel) · 2021 · PMC8620808 · PMID 34835722

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a decreasing trendno p-value reported
In ICU patients who initially presented inflammation but later developed iron deficiency, hepcidin followed a decreasing trend as iron loss progressed [ 86 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.