Targeted Quantification of Carbon Metabolites Identifies Metabolic Progression Markers and an Undiagnosed Case of SDH-Deficient Clear Cell Renal Cell Carcinoma in a German Cohort.

Metabolites · 2021 · PMC8624007 · PMID 34822422

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highly significantno p-value reported

Differences between high and low TNM stage were highly significant for 2HG, citrate, succinate, and lactate, followed by aspartate, asparagine, and glutamine ( Figure 2 ). α-KG did not show significance after excluding necrotic samples.

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