Given these findings, we hypothesized that there may be significant associations between the Li response and these three circadian/clock genes ( RORA, TIMELESS and PPARGC1A ) and that these genes may be plausible candidates for this proof of principle study.
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A Comparison of Different Approaches to Clinical Phenotyping of Lithium Response: A Proof of Principle Study Employing Genetic Variants of Three Candidate Circadian Genes.
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