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Immunobiological Properties and Clinical Applications of Interleukin-38 for Immune-Mediated Disorders: A Systematic Review Study.

Int J Mol Sci · 2021 · PMC8625918 · PMID 34830435

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a decreasing trendno p-value reported
As a matter of fact, in high concentrations of IL-38, there is a decreasing trend for its inhibitory effects.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.