The Lifetime Cost Estimation of Human Papillomavirus-related Diseases in China: A Modeling Study.

J Transl Int Med · 2021 · PMC8629412 · PMID 34900631

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a decreasing trendno p-value reported

In contrast, the costs of HPV-related cancers exhibited a decreasing trend with increasing disease stage; the treatment cost of carcinoma in situ was the highest, whereas the treatment costs of local and distant metastases decreased successively.

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an increasing trendno p-value reported

Our results also showed that the average annual treatment costs per patient of CIN/VaIN caused by HPV exhibited an increasing trend with increasing lesion grade; that is, the more serious the intraepithelial neoplasia, the higher the lifetime treatment cost.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.