WNK3 sh2: NKCC1, p = 0.9121, KCC2, p = 0.5934; n = 3 batches of cultures; Figures 3C,D ) between control and WNK3 knockdown neurons, although there seems to be a slight decreasing trend in the expression of NKCC1 and an increasing trend in the expression of KCC2 in WNK3 knockdown neurons ( Figure 3A ).
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WNK3 Maintains the GABAergic Inhibitory Tone, Synaptic Excitation and Neuronal Excitability <i>via</i> Regulation of KCC2 Cotransporter in Mature Neurons.
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