Also, CD147 induces extracellular matrix metalloproteinases (MMPs), which may be significant while considering the role vasculature, primarily endothelial dysfunction, in promoting pulmonary fibrosis, one of the most detrimental COVID-19 complications ( Ahmetaj-Shala et al., 2020 ).
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CD147-spike protein interaction in COVID-19: Get the ball rolling with a novel receptor and therapeutic target.
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