borderline significantP = 0.05
Outcomes of LBBAP as CRT in LBBB vs Non-LBBB Pooled analysis from 2 studies showed a borderline significant difference in mean reduction of paced QRS duration (MD, 20.77 msec; 95% CI, −0.40 to 41.93 msec; P = 0.05; I 2 = 71%), and improvement in LVEF (MD, 6.00%; 95% CI, 0.15-11.84 %; P = 0.04; I 2 = 44%) in patients with underlying LBBB vs patients with underlying non-LBBB ( Fig. 4 ). 19 , 20 Quality assessment and publication bias Quality assessment of the individual studies determined that 8 of the included studies were of good quality with a low risk of bias.