While the microvessel density values were significantly increased in the IS and PL groups up to the 7th day (7.33 ± 1.53/HPF and 27.67 ± 2.08/HPF) and to the 14th day (18.00 ± 2.00/HPF and 23.67 ± 1.53/HPF), a decreasing trend became manifest in the PDA group since the 7th day onwards (20.00 ± 2.00/HPF).
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3D-printed dermis-specific extracellular matrix mitigates scar contraction via inducing early angiogenesis and macrophage M2 polarization.
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