Sphingolipid metabolism in the development and progression of cancer: one cancer's help is another's hindrance.

Mol Oncol · 2021 · PMC8637577 · PMID 34289244

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In children with neuroblastoma, GD2 shed from tumors into the circulation was found to be a highly significant predictor of high‐risk tumors [ 123 ], while the ganglioside profile of patient‐derived melanoma cells was predictive of aggressiveness [ 124 ] and survival [ 125 ].

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