When IP administered with 25 mg kg −1 dosage, the curves of the CPD-3B vehicle and CPD-3B@SOL micelles showed essentially no difference, while the AUC, C max , and half-life time ( t 1/2 β ) increased with slight significance.
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Biodegradable self-assembly micelles significantly enhanced the solubility, biological stability and <i>in vivo</i> antitumor efficacy of Hexylselen.
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