Foot-and-Mouth Disease Virus 3C Protease Antagonizes Interferon Signaling and C142T Substitution Attenuates the FMD Virus.

Front Microbiol · 2021 · PMC8639872 · PMID 34867853

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highly significantno p-value reported

In addition, if there is a highly significant impact of FMDV 3C pro mediated eIF4AI and eIF4G cleavage on RIG-I and MDA5 expression levels due to the translation inhibition, there should be a reduction in the expression levels of type-I IFN pathway associated other proteins.

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