Therapeutic vulnerability to PARP1,2 inhibition in RB1-mutant osteosarcoma.

Nat Commun · 2021 · PMC8642453 · PMID 34862364

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highly significantno p-value reported

1a ), yielding a highly significant differential median sensitivity assessed using AUC values (Fig. 1b ) in lines with known RB1 -mutant status and/or lacking detectable RB1 expression (Fig. 1l ), compared to RB1-normal lines.

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