However, after the corneal limbal region was scraped, the difference between the levobunolol and control groups was highly significant throughout the wound healing process (Fig. 1 C, D).
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β-blocker eye drops affect ocular surface through β2 adrenoceptor of corneal limbal stem cells.
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After central region debridement, the corneal epithelial healing rate of the levobunolol-treated group exhibited a marginally significant difference compared with the control group (Fig. 1 A, B).
A P value less than 0.05 was considered statistically significant, a P value less than 0.01 was considered extremely significant.