Barely Significant
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Pericardial Adipose Tissue-Derived Leptin Promotes Myocardial Apoptosis in High-Fat Diet-Induced Obese Rats Through Janus Kinase 2/Reactive Oxygen Species/Na+/K+-ATPase Signaling Pathway.

J Am Heart Assoc · 2021 · PMC8649551 · PMID 34482701

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may not be significantno p-value reported
Hence, as an initial form of HF, elevation of cardiac leptin in obesity may not be significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.