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Spatiotemporal trends of the global burden of melanoma in 204 countries and territories from 1990 to 2019: Results from the 2019 global burden of disease study.

Neoplasia · 2022 · PMC8649617 · PMID 34872041

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a decreasing trendno p-value reported
In contrast, when the EAPC estimation and the upper boundary of its 95% CI were both <0, the ASR was in a decreasing trend.

also in 47,180 other papers

an increasing trendno p-value reported
In this study, when the EAPC estimation and the lower boundary of its 95% CI were both >0, we considered the ASR as an increasing trend during the specified period.

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.