highly significantp ≤ 0.01
Thereby, data were marked as significant if p -values were less than 0.05 (* p ≤ 0.05) and highly significant if p -values were less than 0.01 (** p ≤ 0.01) or less than 0.001 (*** p ≤ 0.001) and graphed as mean ± standard deviation. 3.