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Clinical trials in amyotrophic lateral sclerosis: a systematic review and perspective.

Brain Commun · 2021 · PMC8659356 · PMID 34901853

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an encouraging trendno p-value reported
There is, however, an encouraging trend towards the use and development of biomarkers in more recent trials.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.