Metabolic syndrome is associated with prostate enlargement: a systematic review, meta-analysis, and meta-regression on patients with lower urinary tract symptom factors.

Ther Adv Endocrinol Metab · 2021 · PMC8664322 · PMID 34900218

Europe PMC DOI

hedged sentences

0.0560

closest p · 1.1× alpha

0.0560

boldest claim

The sentences

almost significantp = 0.056so close (0.05 < p ≤ 0.1)

No significant association between MetS and IPSS, and Qmax was found; however, there was an almost significant association with PSA (MD = 0.24 ng/ml, p = 0.056). 91 Li et al. 92 also significantly associated MetS with higher annual prostate growth rate and prostate volume; no association was found between MetS and IPSS/IPSS subgroups.

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highly significantno p-value reported

We generated another forest plot for TPV and MetS (total of 30 studies), which proved highly significant, albeit heterogeneity was high: I 2 96.3% [95.4%; 96.9%].

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