The BH3-only protein NOXA serves as an independent predictor of breast cancer patient survival and defines susceptibility to microtubule targeting agents.

Cell Death Dis · 2021 · PMC8668920 · PMID 34903710

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highly significantno p-value reported

Of note, mRNA levels of BOK, implicated in endoplasmic reticulum stress induced apoptosis [ 35 ], also showed a highly significant prognostic value in uni- and multivariate analysis (Tables 1 , 2 ), but not the TCGA data set.

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