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<i>In situ</i> Metabolomics of Metabolic Reprogramming Involved in a Mouse Model of Type 2 Diabetic Kidney Disease.

Front Physiol · 2021 · PMC8670437 · PMID 34916961

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an increasing trendno p-value reported
Further, IHC staining of SAT1 indicated an increasing trend in tubulars in db/db mice kidney, and the subsequent IHC assay of HDC and FAS showed that they were upregulated in both glomeruli and tubulars of db/db mice.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.