Unexplored Excipients in Biotherapeutic Formulations: Natural Osmolytes as Potential Stabilizers Against Thermally Induced Aggregation of IgG1 Biotherapeutics.

An increase in protein aggregation due to thermal stress in the SE-HPLC results was also reflected by an overall trend of increase in hydrodynamic diameter (D h ) for all samples at the end of the accelerated stability study for both mAb A and B (Figure 3 ).

also in 4,871 other papers