Structural Analysis on the Severe Acute Respiratory Syndrome Coronavirus 2 Non-structural Protein 13 Mutants Revealed Altered Bonding Network With TANK Binding Kinase 1 to Evade Host Immune System.

The average RMSD for M429I was 0.65Å; however, an increasing trend was reported – for instance, a previous study reported that mutations with increasing instability produce the function of radical protein, implying that these mutations have evolved with radical function and have increased infectivity ( Hussain et al., 2020 ).

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