PP2A phosphatase inhibition is anti-fibrotic through Ser77 phosphorylation-mediated ARNT/ARNT homodimer formation.

Sci Rep · 2021 · PMC8674365 · PMID 34912030

Europe PMC DOI

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a positive trendno p-value reported

failed to reach significanceno p-value reported

While combinations of FK506/ LB100 and GPI1046/ LB100 were equally effective, the addition of LB100 to GPI1046 failed to reach significance, as compared to GPI1046 monotherapy, even though a positive trend was observed.

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