Biased M1 muscarinic receptor mutant mice show accelerated progression of prion neurodegenerative disease.

Proc Natl Acad Sci U S A · 2021 · PMC8685681 · PMID 34893539

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a nonsignificant trendno p-value reported

However, we did detect a nonsignificant trend for reduced phosphorylation of ERK1/2 in the hippocampus of prion-infected M1-PD versus M1-WT mice, which may warrant further investigations.

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